Megaloblastic Anaemia and Subacute Combined Degeneration from Tuberculous Disease of the Small Intestine

Malignant Gout with Tophaceous Small Intestine and Megaloblastic Anaemia.

Gout, like diabetes, is worst in youth. Often impossible to control by uricosuiric drugs, it may cause premature death. Such was the case of a man described by Kersley, Mandel, and Jeffrey (1950). He developed gout at 18 years, became crippled at 21, and died at 24 from bronchopneumonia, associated with a tophus in the atlas vertebra. His brother, who came under our care, also developed gout at...

Subacute combined degeneration : report of two cases

Subacute combined degeneration ( SCD) due to vitamin B12 deficiency is common in North of Europe but sometimes it is seen in Iran. It can develop before the symptoms of anemia is obvious, with myelin injury and then axon and even neuron destruction in spinal cord, brain, optic and peripheral nerves. In this study two cases are reported; in the first patient, this disease in manifested by vitami...

Subacute combined degeneration.

Amino-aciduria accompanying untreated pernicious anaemia and subacute combined degeneration of the spinal cord.

Weaver and Neill (1954) reported abnormal excretions of taurine, sometimes accompanied by over-excretion of lysine, cystine, and leucine, in the urine of five patients suffering from pernicious anaemia. In one patient with subacute combined degeneration of the spinal cord in whom the blood picture was normal, they found that taurine alone was excreted in abnormal quantities. After treatment wit...

SUBACUTE combined degeneration of the spinal cord.

This paper describes the clinical history of an adult male who was found to be suffering from subacute combined degeneration of the spinal cord. It is believed that this is the first report of this condition in Papua New Guinea.